Skip to main content
. 2012 Dec;86(24):13423–13433. doi: 10.1128/JVI.02171-12

Fig 7.

Fig 7

Effect of M250I mutation on p24 helix 6. (A) N-terminal domain of p24 (PDB ID 1AK4 [23]) showing helix 6 (in color) and positions 248 (cyan) and 250 (red). (B) Conformation predicted for the wild-type HIV-1 subtype B helix 6 peptide. (C) Conformation predicted for the M250I variant. (D) Conformation predicted for the wild-type HIV-1 subtype C helix 6 peptide. (E) Conformation predicted for the M250I variant. In all panels, the residue at position 248 is shown in cyan and that at position 250 is shown in red. Stick representations are also shown at residue positions 248 and 250. In panels B and C, the helix 6 peptide has a glycine at position 248, and in panels D and E it has an alanine. The images were rendered using Pymol (www.pymol.org).