Table 2.
Group | n | GIR (mg·kg−1·min−1) |
AUCG0–60
(mmol·L−1·min−1) |
AUCI0–10
(mIU·L−1·min−1) |
AUCI10–60
(mIU·L−1·min−1) |
AUCI0–60
(mIU·L−1·min−1) |
---|---|---|---|---|---|---|
NC | 5 | 7.80 ± 0.51 | 57.12 ± 5.38 | 277.29 ± 5.46 | 94.57 ± 2.35 | 371.85 ± 5.97 |
HF | 5 | 5.32 ± 0.90* | 73.63 ± 6.69* | 264.46 ± 3.51* | 159.67 ± 7.98* | 424.13 ± 9.20* |
HF+S | 5 | ND | 180.79 ± 7.31∗# | 122.84 ± 11.84∗# | 94.65 ± 24.67# | 217.49 ± 35.67∗# |
HF+T+S | 5 | ND | 122.68 ±18.44∗#∇ | 198.13 ± 13.12∗#∇ | 124.88 ± 7.80∗#★ | 326.01 ± 19.68∗#∇ |
NC: normal control group; HF: high-fat diet group; HF+S: high-fat diet plus STZ intraperitoneal injection group; HF+T+S: high-fat diet plus telmisartan intervention and STZ intraperitoneal injection group.
GIR: glucose infusion rate; AUCG: area under the curve of glucose; AUCI: area under the curve of insulin.
● P < 0.05; *P < 0.01 as compared with NC group; ▲ P < 0.05, #<0.01 as compared with HF group; ★<0.05, ∇<0.01 as compared with HF+S group.