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. 2012 Nov 12;2012:618923. doi: 10.1155/2012/618923

Table 3.

Quantitive analysis of RT-PCR and immunohistochemistry results (x¯±s).

Group n ARC ILRC IRC ICD NRC CRC AC
NC 5 0.73 ± 0.20 0.57 ± 0.13 −4.14 ± 0.14 2.51 ± 0.26 −5.02 ± 0.19 −5.18 ± 0.11 0.21 ± 0.05
HF 5 1.61 ± 0.19* 1.57 ± 0.22* −5.20 ± 0.09* 2.37 ± 0.08 −3.99 ± 0.33* −4.19 ± 0.12* 0.72 ± 0.10*
HF+S 5 1.95 ± 0.11∗# 1.93 ± 0.17∗# −5.42 ± 0.07∗# 1.45 ± 0.14∗# −3.40 ± 0.14∗# −3.84 ± 0.11∗# 0.98 ± 0.04∗#
HF+T+S 5 1.72 ± 0.14∗★ 1.67 ± 0.11∗★ −5.33±0.05∗▲★ 1.78 ± 0.12∗#∇ −3.62 ± 0.12∗▲★ 4.02 ± 0.07∗▲★ 0.84 ± 0.06∗▲∇

ARC: AT1R mRNA relative content; ILRC: IL-1β mRNA relative content; IRC: insulin raltive concentration; ICD: insulin positive cell density; NRC: NF-κB relative concentration; CRC: caspase-3 relative concentration; AC: apoptosis cells of unit islet area.

NC: normal control group; HF: high-fat diet group; HF+S: high-fat diet plus STZ intraperitoneal injection group; HF+T+S: high-fat diet plus telmisartan intervention and STZ intraperitoneal injection group.

P < 0.05; *P < 0.01 as compared with NC group; P < 0.05, #<0.01 as compared with HF group; <0.05, <0.01 as compared with HF+S group.