Table 2.
Clinical and radiological predictors of CIS conversion to MS after 2 years.
| Demographic data | CIS cohort | MS cohort | P value |
|---|---|---|---|
| (n = 39) | (n = 58) | ||
| Sex | |||
| Female | 21 (21.6%) | 34 (35.1%) | 0.4 |
| Male | 18 (18.6%) | 24 (24.7%) | 0.08 |
|
| |||
| Age (mean ± SD) | 30.21 ± 6.70 | 24.64 ± 6.77 | 0.01* |
|
| |||
| Age | |||
| <30 years | 18 (18.6%) | 45 (46.4%) | 0.002* |
| ≥30 | 21 (21.6%) | 13 (13.4%) | 0.23 |
|
| |||
| Age at onset (mean ± SD) | 25.59 ± 6.89 | 21.62 ± 6.15 | 0.01* |
|
| |||
| Age at onset | |||
| <30 years | 24 (24.7%) | 49 (50.5%) | 0.01* |
| ≥30 | 15 (15.5%) | 9 (9.3%) | 0.2 |
|
| |||
| Clinical presentation | |||
| Optic nerve | 6 (6.2%) | 11 (11.3%) | 0.4 |
| Brainstem/cerebellum | 8 (8.2%) | 15 (15.5%) | 0.4 |
| Spinal cord | 11 (11.3%) | 19 (19.3%) | 0.5 |
| Supratentorial | 13 (13.4%) | 18 (18.6%) | 0.4 |
|
| |||
| Number of lesions in MRI | |||
| No lesion | (2.1%) | 0 (0%) | |
| 1–3 lesions | 16 (16.5%) | 2 (3.4%) | 0.001* |
| 4–8 lesions | 16 (16.5%) | 21 (21.7%) | 0.2 |
| ≥9 lesions | 5 (5.2%) | 35 (36.1%) | 0.002* |
∗Statistically significant.