Figure 3.

Representative binding sites of small molecules and peptides in antiparallel double-layer β-sheet protofibrils (left) modeled by Wu et al.¹⁰² and model parallel β-strands (right) similar to those considered by Convertino et al.⁹⁹ The parallel β-sheet structure is also used to illustrate the approximate binding sites of the indicated molecules to antiparallel β-sheet models considered by Viet et al.⁶⁵ and Liu et al.¹⁰¹