Table 1. Differences in Basal Levels of Protein Expression in WT and kin- S49 Cells^a.

	kin- ctrl:WT ctrl
gene	accession number	average ratio	unique_pep	spectrum_num	protein
Regulation of Transcription
Anp32a	IPI00314736	3.62	2	30	acidic leucine-rich nuclear phosphoprotein 32 family member A
Txn1	IPI00226993	2.49	2	50	thioredoxin
Supt5h	IPI00453975	1.70	2	24	isoform 2 of transcription elongation factor SPT5
Morf4l2	IPI00463666	0.63	2	10	mortality factor 4-like protein 2
Lrpprc	IPI00420706	0.33	2	12	leucine-rich PPR motif-containing protein
Adenyl Nucleotide Binding
Gsr	IPI00760002	2.39	3	30	glutathione reductase
Ube1y1	IPI00123313	0.59	10	54	Ube1x ubiquitin-activating enzyme E1 X
Psmc3	IPI00758064	0.54	3	17	proteasome (Prosome, macropain) 26S subunit ATPase 3
Rpsa-ps7	IPI00677305	4.55	7	287	similar to 40S ribosomal protein SA
Etfb	IPI00121440	3.48	2	47	electron transfer flavoprotein subunit β
Tsnax	IPI00137296	2.72	2	17	translin-associated protein X
Tnpo3	IPI00464114	2.44	4	49	isoform 1 of transportin-3
Glyr1	IPI00817029	2.00	2	4	putative oxidoreductase isoform 1
Snrpd3	IPI00119224	1.92	4	236	small nuclear ribonucleoprotein Sm D3
Gm4492	IPI00853739	1.90	4	65	Gm4492 similar to gag
Lgals1	IPI00229517	1.81	3	114	galectin-1
Plrg1	IPI00331172	0.61	2	18	pleiotropic regulator 1
Lrrc59	IPI00123281	0.58	2	17	leucine-rich repeat-containing protein 59
Anxa5	IPI00317309	0.10	2	8	Annexin A5

^aProteins whose levels of expression differ between kin- and WT S49 cells under basal (control, ctrl) conditions are listed. The proteins are classified according to the DAVID bioinformatics software. The data shown are the average ratios (kin- ctrl:WT ctrl) from at least two biological replicates. The data for proteins whose expression is increased in kin- cells are shown in bold; proteins with decreased expression in kin- cells are shown in italics. Also shown are the number of unique peptides identified for each protein (unique_pep) and the number of PQD spectra (spectrum_num) used for each protein quantitation.