Table 2.
Allele frequencies and estimated odds ratios for rs1361549 in African American, European American, and Puerto Rican cases and controls. Comparisons for African American and Puerto Rican cases and controls are shown for individuals regardless of local ancestry (all), individuals homozygous for African ancestry (African Ancestry), individuals heterozygous for African/European or African/Native American ancestry (African/European Ancestry, African/Non-African Ancestry), and individuals homozygous for non-African ancestry (Native American or European ancestry).
| Sample | Frequency in Cases (N) | Frequency in Controls (N) | Odds Ratio (95% CI) |
|---|---|---|---|
| HapMap YRI | - | 0 (120) | - |
| African Americans (all) | 0.09 (355) | 0.07 (444) | 1.4 (0.98–2.1) |
| African Ancestry | 0 (243) | 0 (257) | - |
| African/European Ancestry | 0.27 (104) | 0.14 (165) | 2.2 (1.4–3.5) |
| European/European Ancestry | 0.63 (8) | 0.27 (22) | 4.3 (1.2–18) |
| European Americans | 0.42 (678) | 0.40 (561) | 1.1 (0.9–1.3) |
| Puerto Ricans (all) | 0.31 (277) | 0.29 (191) | 1.1 (0.79–1.4) |
| African Ancestry | 0 (21) | 0 (3) | - |
| African/Non-African Ancestry | 0.20 (73) | 0.11 (47) | 2.1 (0.92–5.0) |
| Non-African Ancestry | 0.38 (183) | 0.36 (141) | 1.1 (0.78–1.5) |
| HapMap CEU | - | 0.42 (120) | - |
CI = 95% confidence interval.