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. Author manuscript; available in PMC: 2012 Nov 21.
Published in final edited form as: Chembiochem. 2011 Jun 10;12(11):1767–1773. doi: 10.1002/cbic.201100007

Table 1.

Kinetic data for inhibition of human DCTPP1 by triptolide and analogs. Substrate in all cases was 5-I-dCTP.

Inhibitor Ki ± SE (μm)
Triptolide 1 168 ± 17
Triptonide 4 135 ± 20
Triptriolide 5 85 ± 7
5-hydroxytriptonide 6 356 ± 96
14-α-triptolide 7 194 ± 28