Figure 2.

Protein network and pathway structure for biologically informative priors in the synthetic response data study. Responses were generated from published phospho-proteomic data [10] consisting of 11 proteins and 853 samples (baseline data only). Network structure shown here is based on that given in Sachs et al.[10] and reflects current knowledge of signalling interactions. Proteins were divided into four pathways, denoted by node colours red, blue, green and yellow. The grey nodes are each members of all four pathways.