Table 4.
Correlation between PGI-I and other BPH Measures (change from baseline) in all patients
| PGI-I (last visit) | n (%) | Mean IPSS change (SD) | Mean IPSS-QoL change (SD) | Mean BII change (SD) | Mean Qmax change (SD) |
|---|---|---|---|---|---|
| Very Much Better |
99 (6.1%) |
−14.4 (5.9) |
−2.6 (1.6) |
−5.2 (3.1) |
3.7 (4.9) |
| Much Better |
443 (27.2%) |
−10.9 (5.6) |
−2.0 (1.3) |
−4.0 (2.9) |
4.0 (5.6) |
| A Little Better |
632 (38.8%) |
−7.0 (5.4) |
−1.0 (1.2) |
−2.3 (2.7) |
3.0 (5.0) |
| No Change |
357 (21.9%) |
−3.3 (5.2) |
−0.3 (1.1) |
−0.9 (2.7) |
2.1 (4.3) |
| A Little Worse |
65 (4.0%) |
−0.2 (5.7) |
0.0 (1.2) |
−0.1 (3.0) |
2.0 (4.8) |
| Much Worse |
26 (1.6%) |
3.5 (5.4) |
0.5 (1.1) |
1.8 (2.6) |
1.3 (3.1) |
| Very Much Worse |
6 (0.4%) |
6.8 (5.1) |
1.0 (0.9) |
4.5 (2.1) |
0.1 (2.0) |
| Overall comparison p-value |
|
<0.001 |
<0.001 |
<0.001 |
<0.001 |
| Pairwise comparison p-value |
|
|
|
|
|
| Better vs. No change |
|
<0.001 |
<0.001 |
<0.001 |
<0.001 |
| Better vs. Worse |
|
<0.001 |
<0.001 |
<0.001 |
0.002 |
| No change vs. Worse |
|
<0.001 |
<0.001 |
<0.001 |
0.534 |
| Spearman’s Correlation | 0.56** | 0.53** | 0.47** | −0.15** |
PGI-I: Patient Global Impression of Improvement; IPSS: International Prostate Symptom Scores; IPSS QoL: IPSS-Quality of Life (QoL), BII - Benign Prostatic Hyperplasia Impact Index; Qmax: peak urine flow rate; n: number of patients; SD: Standard Deviation. Overall and pairwise comparison p-values are from analysis of variance without adjusting for covariates. **: p<0.001.