Table 4.
Unique effects of insulin neutralization on differential gene expression
|
Up-regulated genes |
|
Down-regulated genes |
|
||
|---|---|---|---|---|---|
| Gene symbol | Gene title | Fold change | Gene symbol | Gene title | Fold change |
| GCG |
Glucagon |
2.91 |
LOC425670 |
glucagon receptor precursor |
2.77 |
| TCP11L2 |
t-complex 11 (mouse)-like 2 |
2.08 |
BAK1 |
BCL2-antagonist/killer 1 |
1.83 |
| LOC416916 |
hypothetical LOC416916 |
1.98 |
CCT3 |
chaperonin containing TCP1, subunit 3 (gamma) |
1.62 |
| MAGI1 |
membrane associated guanylate kinase, WW and PDZ domain containing 1 |
1.84 |
SETD7 |
SET domain containing (lysine methyltransferase) 7 |
1.62 |
| SEPT10 |
septin 10 |
1.79 |
ST13 |
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
1.62 |
| LSM14A |
LSM14A, SCD6 homolog A (S. cerevisiae); similar to LSM14 homolog A (SCD6, S. cerevisiae) |
1.71 |
AHSA1 |
AHA1, activator of heat shock 90 kDa protein ATPase homolog 1 (yeast) |
1.62 |
| |
|
|
TOE1 |
target of EGR1, member 1 (nuclear) |
1.59 |
| AZIN1 | antizyme inhibitor 1 | 1.56 | |||
FDR p-value <0.05.