Table 2.
Echocardiographic findings in the three groups
|
ARVC (n = 17) |
Relatives (n = 19) |
Controls (n = 22) |
P-value* | |
|---|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | ||
|
LV diameter (mm) |
52.6 (6.4) |
54.6 (4.4) |
51.3 (2.9) |
0.009 |
|
RVOT/BSA (cm/m2) |
2.0 (0.4) |
1.6 (0.2) |
1.6 (0.2) |
0.981 |
|
RVIT/BSA (cm/m2) |
2.3 (0.5) |
1.9 (0.2) |
1.8 (0.2) |
0.674 |
|
LVOT VTI (cm) |
18.8 (5.5) |
21.3 (2.5) |
20.9 (2.4) |
0.555 |
|
TAPSE (mm) |
19.1 (5.0) |
25.3 (2.9) |
25.3 (3.0) |
0.963 |
|
Sw lat. LV (cm/s) |
6.6 (2.3) |
7.3 (1.2) |
8.5 (1.9) |
0.018 |
|
Sw Sept. (cm/s) |
5.7 (1.6) |
6.6 (1.0) |
7.1 (0.9) |
0.115 |
|
Sw RV free wall (cm/s) |
8.2 (2.5) |
11.2 (1.9) |
11.6 (1.7) |
0.545 |
|
E/A LV |
1.3 (0.5) |
1.8 (0.6) |
1.7 (0.4) |
0.600 |
|
E/E’ LV |
8.8 (3.2) |
6.4 (2.1) |
6.1 (1.6) |
0.608 |
|
2D strain LV base (%) |
−17.3 (4.4) |
−19.6 (2.7) |
−20.2 (3.5) |
0.518 |
|
2D strain LV mid (%) |
−15.3 (4.9) |
−18.3 (3.2) |
−18.3 (2.4) |
0.968 |
|
2D strain sept base (%) |
−14.9 (3.6) |
−15.8 (2.9) |
−17.8 (2.5) |
0.025 |
|
2D strain sept mid (%) |
−15.2 (5.6) |
−18.5 (2.9) |
−18.2 (2.1) |
0.636 |
|
2D strain RV base (%) |
−16.0 (6.8) |
−26.8 (2.9) |
−28.5 (3.6) |
0.121 |
| 2D strain RV mid (%) | −18.9 (5.9) | −27.3 (4.5) | −27.2 (3.5) | 0.945 |
* Controls vs. relatives using Student’s t-test.
Right ventricular outflow and inflow diameter related to BSA(RVOT/BSA resp.RVIT/BSA), Left ventricular outflow velocity time integral (LVOT VTI), tricuspid annular plane systolic excursion (TAPSE), systolic velocity at AV-plane in lateral LV (SwLV), septum (Sw sept) and RV wall (Sw RV).