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In vivo blood clearance and tumour uptake of the Antp-p21 fusion protein. Radiolabelled Antp-p21 was injected into SKOV-3 tumour-bearing nude mice and the blood (●) and tumour (○) was counted over 6 hours. The percentage of injected dose per gram of tissue is plotted and fit to a bi-exponential decay curve. For the blood clearance, the decay curve yielded a beta-phase half-life value of 4.6 hours.
