Table 2.
The mRNA levels of IGF-1, IGF-1R, IGF-2, IGF-2R, IGFBP-3, ERα and ERβ in EAC, tumor-adjacent, and control groups
| groups | n | IGF-1 | IGF-1R | IGF-2 | IGF-2R | IGFBP-3 | ERα | ERβ |
|---|---|---|---|---|---|---|---|---|
| Control |
42 |
0.58 ± 0.30 |
0.54 ± 0.32 |
0.33 ± 0.19 |
0.04 ± 0.03 |
4.58 ± 3.35 |
16.24 ± 10.10 |
50.10 ± 21.60 |
| EAC |
58 |
1.19 ± 00.79* |
6.23 ± 3.98* |
2.44 ± 2.32* |
4.32 ± 2.98* |
14.47 ± 12.31* |
10.67 ± 7.63 |
31.44 ± 25.22 |
| Tumor-adjacent | 31 | 2.66 ± 01.73# | 35.34 ± 22.02# | 8.59 ± 7.13# | 0.39 ± 0.36# | 8.28 ± 4.57# | 45.54 ± 33.58# | 529.62 ± 269.7# |
*p < 0.05 vs control,#P < 0.05 vs EAC (endometrioid adenocarcinoma) by one-way ANOVA.