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. 2012 Nov 21;7(11):e50098. doi: 10.1371/journal.pone.0050098

Figure 2. Exogenous ARTN modulates HMEC-1 cell behaviour.

Figure 2

(A) The expression of ARTN, GRFα1-4 and RET in HMEC-1 cells determined by quantitative real time PCR. Cellular behaviour of HMEC-1 cells, including, (B) Monolayer proliferation. (C) Cell migration. (D) Cell invasion. (E) in vitro tubule formation on matrigel were assessed in the presence of different concentration of recombinant ARTN. Recombinant ARTN was added at the indicated concentrations every two days. *, p<0.05; **, p<0.01.