Table 2.
The mRNA expression of TGFβ/Smads in different cell lines and mice models
| |
Cell line/ Models |
MHCC97H or L |
2-△△Ct (MEAN±SD) |
95%CI |
P value |
|
|---|---|---|---|---|---|---|
| Lower bound | Higher bound | |||||
| TGFβ |
Cell line |
MHCC97H |
0.18±0.15 |
0.07 |
0.29 |
|
| |
|
MHCC97L |
0.40±0.19 |
0.26 |
0.52 |
0.011# |
| |
Models |
MHCC97H |
1.24±0.96 |
0.78 |
1.69 |
|
| |
|
MHCC97L |
2.81±1.61 |
1.73 |
3.89 |
0.002* |
| Smad2 |
Cell line |
MHCC97H |
0.99±0.17 |
0.50 |
1.56 |
|
| |
|
MHCC97L |
2.56±0.66 |
1.38 |
2.91 |
0.047# |
| |
Models |
MHCC97H |
1.18±0.73 |
0.84 |
1.53 |
|
| |
|
MHCC97L |
1.52±0.42 |
1.23 |
1.80 |
0.172* |
| Smad7 |
Cell line |
MHCC97H |
12.36±1.62 |
8.32 |
16.40 |
|
| |
|
MHCC97L |
46.98±30.39 |
−28.52 |
122.48 |
0.187# |
| |
Models |
MHCC97H |
1.18±0.62 |
0.88 |
1.46 |
|
| MHCC97L | 1.48±0.90 | 0.87 | 2.08 | 0.275* | ||
Students’ t test was used to assess the statistical significance of differences between two groups. 95%CI: 95% Confidence Interval for Mean, SD=standard deviation, # compared with MHCC97-H cell line; * compared with MHCC97-H model.