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. 2012 Nov 21;7(11):e49889. doi: 10.1371/journal.pone.0049889

Figure 1. Rhodopsin expression in mice with various numbers of rhodopsin genes.

Figure 1

(A) Northern blot analysis of rhodopsin mRNA from various mouse lines. Copy numbers of wild type rhodopsin and P23H-rhodopsin genes are indicated below each lane, where mRho 0 is mRho−/−, mRho 1 is mRho+/−, mRho 2 is mRho+/+, and mRho 0 NHRE 2 is mRho−/−NHRE+/+. Quantification of the 18S and 26S rRNAs bands from the agarose gels prior to transfer (shown as a negative below the Northerns) served as loading controls. Six retinas were used to prepare each mRNA sample. Northern images were obtained on a PhosphorImager. Sizes are indicated in kb.