. 2012 Aug 6;12:39. doi: 10.1186/1471-2466-12-39

Table 4.

Multivariate logistic regressions: Odds ratio for associations between each clinical subtype and treatment subgroups (first line of each cell in a row) and each treatment subgroup and clinical subtypes (second line of each cell in a column, in italic)

Odds ratio	*Trt type 1*	*Trt type 2*	*Trt type 3*	*Trt type 40*	*Trt type 5*	*Trt type 6*
Odds ratio	Nebulised treatments	Fixed combinations	LABA and inhaled corticosteroids prescribed separately	Non-invasive ventilation and oxygen therapy	Fixed combinations of short acting anticholinergic and β2 agonist	Flu and pneumococcal vaccines
Clinical type 1
Exposed but not severely impaired patients	0.611³	0.713¹	0.581¹	0.198⁴	0.592²	0.575³
Exposed but not severely impaired patients	*0.636*²	0.800⁰	*0.686*¹	*0.255*³	*0.637*²	*0.500*⁴
Clinical type 2
Overweight smokers with comorbidities	0.781⁰	0.907⁰	0.891⁰	3.625⁴	1.060⁰	0.581²
Overweight smokers with comorbidities	0.877⁰	0.939⁰	1.004⁰	*4.396*⁴	1.221⁰	0.762⁰
Clinical type 3
Severe airflow obstruction	1.636³	1.605³	1.580¹	6.214⁴	1.382¹	1.606³
Severe airflow obstruction	*1.683*⁴	*1.455*³	1.207⁰	*7.381*⁴	*1.381*²	*2.095*⁴
Clinical type 4
Women	1.142⁰	0.952⁰	1.293⁰	0.821⁰	1.250⁰	1.105⁰
Women	1.097⁰	0.868⁰	1.274⁰	1.101⁰	1.254⁰	1.194⁰
Clinical type 5
Symptoms of chronic bronchitis	1.116⁰	0.986⁰	0.868⁰	1.117⁰	1.095⁰	2.210⁴
Symptoms of chronic bronchitis	1.161⁰	1.083⁰	0.912⁰	1.243⁰	1.107⁰	*2.221*⁴
Clinical type 6
Elderly patients with cardiovascular comorbidity	0.686²	1.335¹	1.022⁰	1.308⁰	0.954⁰	1.441²
Elderly patients with cardiovascular comorbidity	*0.733*¹	*1.323*¹	0.899⁰	1.200⁰	1.087⁰	*1.351*¹

All models included the 6 treatment or clinical subtypes as covariates. Figures in bold are significantly different from 1 and exponent indicates the class of p values of the log-likelihood test: ⁰ for p > 0.05, ¹ for p ≤ 0.05, ² for p < 0.01, ³ for p < 0.001 and ⁴ for p < 0.0001.