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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Dev Dyn. 2012 Oct 25;241(12):1922–1932. doi: 10.1002/dvdy.23877

Figure 3.

Figure 3

mpp5am520 mutant displays structural disorganization of pronephric glomerulus. Pronephric glomerular structure is shown by hematoxylin-eosin stained JB-4 section at 2 dpf (A–C), 3 dpf (D–F), and 4 dpf (G–I). In wild type siblings, a pair of glomerular primordia has merged to form a single glomerulus (arrowheads) beneath the notochord at 2 dpf (A), 3 dpf (D), and 4 dpf (G). In 2 dpf mpp5am520 mutants, a pair of glomerular primordia retains epithelial vesicular structure and does not merge beneath the notochord (arrows in B, C). At 3 and 4 dpf mpp5am520 mutants exhibited still two separated podocyte masses (arrows in E, F, H, I). Scale bar = 10 µm.