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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: J Immunol. 2012 Oct 22;189(11):5206–5211. doi: 10.4049/jimmunol.1200137

Figure 2. Lung CD8 T cell subpopulations display similar effector function.

Figure 2

(Panel A) Spleen and lung cells we isolated from influenza virus infected mice on day 10 after infection. After stimulation with influenza virus-specific NP366-374 peptide or with PMA/ionomycin, we measured intracellular IFNγ production and cell surface CD107a/b mobilization on previously gated KLRG1high and KLRG1low CD8 T cells. Bar diagrams show the frequency of IFNγ+CD107ab−, polyfunctional IFNγ+CD107ab+, and IFNγ−CD107ab+ cells. (Panel A) Spleen CD8 T cells. (Panel B) Lung CD8 T cells. Data are representative from 2 independent experiments with 3 mice/group. Error bars indicate SD. *** p ≤ 0.0005, **** p ≤ 0.00005.