Table 1. Characteristics of the kidneys.
Control Kidneys | |||||||||||
Sex | KidneWeight* | Cortex Weight* | Cortex Volume | Glomeruli # | Mean Glomerular Volume | Total Glomerular Volume | Mean Nephron Volume | Cells per Glomerular Tuft Cross Section | Podocytes Glomerular Tuft Cross Section | Percentage of Podocytes per Glomerular Tuft Cross Section | |
m/f | g | g | ml | n | x10 −3 mm 3 | mm 3 | mm 3 | n | n | % | |
Control-1 | f | 161 | 129 | 128 | 1,226,839 | 5.58 | 9,787 | 0.13 | 115.6 | 21.6 | 18.7 |
Control-2 | m | 162 | 136 | 136 | 812,336 | 5.90 | 6,850 | 0.20 | 138.9 | 19.1 | 13.8 |
Control-3 | m | 166 | 140 | 142 | 1,735,799 | 6.35 | 15,747 | 0.10 | 118.3 | 25.1 | 21.2 |
Control-4 | m | 174 | 153 | 155 | 987,884 | 6.18 | 8,728 | 0.18 | 166.2 | 28.3 | 17.0 |
Control-5 | f | 177 | 152 | 153 | 1,827,757 | 6.67 | 17,409 | 0.10 | 137.0 | 20.1 | 14.7 |
Control-6 | m | 187 | 160 | 162 | 1,856,511 | 5.36 | 9,951 | 0.10 | 111.1 | 18.3 | 16.5 |
Control-7 | f | 193 | 161 | 173 | 2,306,990 | 6.10 | 20,113 | 0.09 | 112.3 | 21.7 | 19.3 |
Mean | 174 | 147 | 149 | 1,536,302 | 6.02 | 12,654 | 0.13 | 128.5 | 22.0 | 17.3 | |
+/− SD | +/−12,4 | +/−12,3 | +/−15,6 | +/−538,809 | +/−0.44 | +/−5,040 | +/−0.05 | +/−20.2 | +/−3.5 | +/−2.6 | |
p-value for comparison | <0.001 | <0.001 | <0.001 | 0.008 | 0.56 | 0.03 | 0.43 | 0.34 | 0.61 | 0.67 | |
Congenital Solitary Functioning Kidneys | |||||||||||
Sex | Kidney Weight * | Cortex Weight * | Cotex Volume | Glomeruli | Mean Glomerular Volume | Total Glomerular Volume | Mean Nephron Volume | Cells per Glomerular Tuft Cross Section | Podocytes Glomerular Tuft Cross Section | Percentage of Podocytes per Glomerular Tuft Cross Section | |
m/f | g | g | ml | n | x10 −3 mm 3 | mm 3 | mm 3 | n | n | % | |
CSFK-1 | f | 275 | 227 | 227 | 2,031,045 | 6.56 | 19,036 | 0.16 | 154.1 | 28.8 | 18.7 |
CSFK-2 | f | 276 | 225 | 231 | 2,208,398 | 5.82 | 18,368 | 0.13 | 174.0 | 31.6 | 18.2 |
CSFK-3 | m | 300 | 251 | 266 | 2,771,222 | 7.28 | 28,833 | 0.11 | 122.1 | 23.3 | 19.1 |
CSFK-4 | m | 325 | 276 | 283 | 1,808,309 | 5.04 | 13,013 | 0.18 | 122.4 | 16.4 | 13.4 |
CSFK-5 | m | 345 | 277 | 282 | 2,624,535 | 5.28 | 19,805 | 0.13 | 96.9 | 17.9 | 18.5 |
CSFK-6 | m | 356 | 298 | 303 | 2,288,602 | 4.50 | 14,703 | 0.16 | 147.6 | 26.0 | 17.6 |
CSFK-7 | m | 380 | 320 | 323 | 2,377,973 | 6.02 | 20,467 | 0.16 | 176.2 | 19.5 | 11.1 |
Mean | 322 | 268 | 274 | 2,301,441 | 5.79 | 19,175 | 0.14 | 141.9 | 23.4 | 16.6 | |
+/− SD | +/−40,5 | +/−35,5 | +/−35,4 | +/−330,670 | +/−0.95 | +/−5,066 | +/−0.02 | +/−29.4 | +/−5.7 | +/−3.1 |
The weight of the fixed tissue is given.
Per kidney. Comparing two control kidneys with one CSFK by multiplying the demonstrated number found in control kidney by 2 would yield a total glomerular number of 3,072,604+/−1,077,619 for controls and 2,301,441+/−330,670 for CSFKs (p = 0.10).