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. 2012 Nov 21;7(11):e49735. doi: 10.1371/journal.pone.0049735

Table 1. Characteristics of the kidneys.

Control Kidneys
Sex KidneWeight* Cortex Weight* Cortex Volume Glomeruli # Mean Glomerular Volume Total Glomerular Volume Mean Nephron Volume Cells per Glomerular Tuft Cross Section Podocytes Glomerular Tuft Cross Section Percentage of Podocytes per Glomerular Tuft Cross Section
m/f g g ml n x10 −3 mm 3 mm 3 mm 3 n n %
Control-1 f 161 129 128 1,226,839 5.58 9,787 0.13 115.6 21.6 18.7
Control-2 m 162 136 136 812,336 5.90 6,850 0.20 138.9 19.1 13.8
Control-3 m 166 140 142 1,735,799 6.35 15,747 0.10 118.3 25.1 21.2
Control-4 m 174 153 155 987,884 6.18 8,728 0.18 166.2 28.3 17.0
Control-5 f 177 152 153 1,827,757 6.67 17,409 0.10 137.0 20.1 14.7
Control-6 m 187 160 162 1,856,511 5.36 9,951 0.10 111.1 18.3 16.5
Control-7 f 193 161 173 2,306,990 6.10 20,113 0.09 112.3 21.7 19.3
Mean 174 147 149 1,536,302 6.02 12,654 0.13 128.5 22.0 17.3
+/− SD +/−12,4 +/−12,3 +/−15,6 +/−538,809 +/−0.44 +/−5,040 +/−0.05 +/−20.2 +/−3.5 +/−2.6
p-value for comparison <0.001 <0.001 <0.001 0.008 0.56 0.03 0.43 0.34 0.61 0.67
Congenital Solitary Functioning Kidneys
Sex Kidney Weight * Cortex Weight * Cotex Volume Glomeruli Mean Glomerular Volume Total Glomerular Volume Mean Nephron Volume Cells per Glomerular Tuft Cross Section Podocytes Glomerular Tuft Cross Section Percentage of Podocytes per Glomerular Tuft Cross Section
m/f g g ml n x10 −3 mm 3 mm 3 mm 3 n n %
CSFK-1 f 275 227 227 2,031,045 6.56 19,036 0.16 154.1 28.8 18.7
CSFK-2 f 276 225 231 2,208,398 5.82 18,368 0.13 174.0 31.6 18.2
CSFK-3 m 300 251 266 2,771,222 7.28 28,833 0.11 122.1 23.3 19.1
CSFK-4 m 325 276 283 1,808,309 5.04 13,013 0.18 122.4 16.4 13.4
CSFK-5 m 345 277 282 2,624,535 5.28 19,805 0.13 96.9 17.9 18.5
CSFK-6 m 356 298 303 2,288,602 4.50 14,703 0.16 147.6 26.0 17.6
CSFK-7 m 380 320 323 2,377,973 6.02 20,467 0.16 176.2 19.5 11.1
Mean 322 268 274 2,301,441 5.79 19,175 0.14 141.9 23.4 16.6
+/− SD +/−40,5 +/−35,5 +/−35,4 +/−330,670 +/−0.95 +/−5,066 +/−0.02 +/−29.4 +/−5.7 +/−3.1
*

The weight of the fixed tissue is given.

#

Per kidney. Comparing two control kidneys with one CSFK by multiplying the demonstrated number found in control kidney by 2 would yield a total glomerular number of 3,072,604+/−1,077,619 for controls and 2,301,441+/−330,670 for CSFKs (p = 0.10).