Figure 1. Histopathologic features of HBV-associated acute liver failure (ALF) showing the severity of hepatic necrosis in 4 patients.

At the time of liver transplantation there was massive hepatic necrosis (MHN) with no viable hepatocytes in Patient 241, MHN (nearly 100%) with few scattered hepatocytes in Patient 31, and submassive hepatic necrosis (SHN) in Patients 219 (70 to 80% necrosis) and 32 (60% necrosis) (hematoxylin and eosin, x400).