Figure 4. ERK5 icKO mice are deficient in olfactory short-term memory.

Mice were presented with cotton swabs laced with the same odorant twice at the indicated time intervals. A different odor was used for each interval time point. The sniffing duration of the cotton swab was recorded for both exposure sessions. A decrease in investigation during the second exposure of the same odorant is suggestive of olfactory memory to the odorant. A) Short-term olfactory memory of control mice. B) Short-term olfactory memory of ERK5 icKO mice. n ≥7 mice per treatment group.