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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Mol Genet Metab. 2012 Aug 8;107(4):650–658. doi: 10.1016/j.ymgme.2012.08.001

TABLE 2.

Cardiovascular malformations of E18.5 fetuses by anatomic defect, sorted by background strain

Cardiovascular Malformation Type
Strain AVS PVS PTA TGA DORV VSD IAA AAA VH DEX BAV COA RAA Total
BTBR, no. 0 1 5 8 11 7 0 16 0 0 3 1 0 52
% 0 1.9 9.6 15.4 21.2 13.5 0 30.8 0 0 5.8 1.9 0 100
C3H, no. 10 0 0 0 1 3 2 0 2 1 0 0 0 19
% 52.6 0 0 0 5.3 15.8 10.5 0 10.5 5.3 0 0 0 100
BL6, no. 4 0 0 0 1 2 6 1 12 0 1 0 1 28
% 14.3 0 0 0 3.6 7.1 21.4 3.6 42.9 0 3.6 0 3.6 100
Total, no. 14 1 5 8 13 12 8 17 14 1 4 1 1 99
% 14.1 1 5.1 8.1 13.1 12.1 8.1 17.2 14.1 1 4 1 1 100

AVS – aortic valve stenosis; PVS – pulmonic valve stenosis; PTA – persistent truncus arteriosus; TGA – transposition of the great arteries; DORV – double outlet right ventricle; VSD – ventricular septal defect; IAA – interrupted aortic arch; AAA – aortic arch anomalies (branching defects); VH – ventricular hypertrophy; DEX – dextrocardia; BAV – bicuspid aortic valve; COA – coarctation of the aorta; RAA – right aortic arch.