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. Author manuscript; available in PMC: 2013 Dec 10.
Published in final edited form as: J Control Release. 2012 Oct 12;164(2):236–246. doi: 10.1016/j.jconrel.2012.10.007

Fig. 6.

Fig. 6

The effect of PEG density on the targeted uptake of labeled nano-emulsions (dh ~100 nm). (A) PEG chains adopt mushroom-like conformations at low density (5 mol%) to provide a semi-permeable layer, but have extended conformations at higher densities; * = RGD ligand. (B,C) Flow cytometry reveals that ligand-enhanced uptake is observed for RGD-labeled nano-emulsions with low PEG chain density, but ligand-mediated and overall cell uptake are both diminished for carriers with higher chain densities. © 2012 American Chemical Society (reprinted with permission) [120].