Table 5.
Comparison of the distribution of the neuronal cytoplasmic inclusions (NCI), neuronal intranuclear inclusions (NII), and dystrophic neurites (DN) based on quantitative data with previously assigned disease subtypes of frontotemporal lobar degeneration with TDP proteinopathy (FTLD-TDP) classified according to the consensus scheme of Cairns et al. [10].
| Frequency of laminar distribution | |||||
|---|---|---|---|---|---|
| Inclusion | Subtype | Upper | Lower | Bimodal | NS |
| cortex | cortex | distribution | |||
| NCI | 1 | 1 | 1 | 0 | 1 |
| 2 | 6 | 0 | 5 | 2 | |
| 3 | 2 | 0 | 1 | 0 | |
| NII | 1 | 0 | 2 | 2 | 2 |
| 2 | 0 | 2 | 5 | 3 | |
| 3 | 2 | 0 | 0 | 3 | |
| DN | 1 | 4 | 0 | 0 | 0 |
| 2 | 1 | 0 | 2 | 2 | |
| 3 | 3 | 1 | 1 | 1 | |
NS = No significant change in abundance across the cortex.