Table 1.
Membrane properties of in vivo olivary neurons under different anaesthetic and genetic conditions.
| Membrane properties | KX anaesthesia (n = 37) | MMF anaesthesia (n =8) | Cx36−/− mutants* (n = 10) | p value |
|---|---|---|---|---|
| Rm (MΩ) | 28.8 (22.3–38.2) | 39.1 (31.7–41.8) | 41.2 (39.8–49.7) | p(KX−Cx36) < 0.05 |
| Cm (pF) | 207.5 (142.4–277.1) | 203.5 (198.3–222.1) | 130.9 (113.1–152.6) | p(KX−Cx36) < 0.05 |
| p(MMF−Cx36) < 0.05 | ||||
| Vm (mV) | −54.0 (−56.8 to −51.0) | −55.0 (−48.0 to −56.0) | −52.8 (−49.9 to −54.4) | ns |
| f (Hz) | 0.44 (0.20–0.58) | 0.24 (0.12–0.44) | 0.47 (0.39–0.59) | ns |
Statistical analyses of basic membrane properties were performed using the Mann–Whitney U-test.
*
Cx36−/− mutant mice were anaesthetized using the KX mixture.
Rm, membrane resistance; Cm, membrane capacitance; Vm, membrane potential; f, firing frequency. All numerical values indicate the median (25–75th percentile).