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Hub residues in salt-bridge networks. The 3D average structure of each FEL basin is shown as cartoon, and the Cα atoms of the residues involved in salt bridges are shown as spheres. The Cα atoms of the interacting residues are connected by sticks, whose thickness is proportional to the persistence of the interaction. Hub residues, defined as those involved in at least three different salt-bridge interactions, are highlighted in yellow.
