Table 2.
Biodistribution of 99mTc-Clomiphene in Swiss albino ascites bearing mice at different time intervals after injection.
| Organs and body fluids | Percent ID/organ | ||||
|---|---|---|---|---|---|
| Time after injection | |||||
| 15 min | 30 min | 1 hr | 4 hr | 24 hr | |
| Blood | 16.5 ± 1.1 | 13.2 ± 0.6 | 8.4 ± 1.3 | 4.3 ± 1.3 | 1.5 ± 0.0 |
| Kidneys | 19.1 ± 0.6 | 16.2 ± 2.5 | 15.4 ± 0.7 | 12.2 ± 1.2 | 3.2 ± 0.0 |
| Liver | 3.7 ± 0.3 | 3.1 ± 0.6 | 2.2 ± 0.6 | 2.0 ± 0.5 | 1.8 ± 0.7 |
| Spleen | 2.5 ± 0.1 | 2.7 ± 0.2 | 2.9 ± 0.1 | 2.9 ± 0.5 | 2.7 ± 0.3 |
| Intestine | 4.6 ± 0.5 | 5.3 ± 0.6 | 6.7 ± 0.4 | 7.3 ± 1.1 | 7.8 ± 0.5 |
| Stomach | 6.2 ± 0.3 | 8.4 ± 1.8 | 9.3 ± 0.8 | 11.6 ± 1.2 | 7.8 ± 0.5 |
| Lungs | 7.5 ± 0.1 | 4.3 ± 0.5 | 2.6 ± 0.2 | 1.9 ± 0.3 | 1.4 ± 0.2 |
| Heart | 8.0 ± 0.3 | 7.1 ± 1.2 | 2.2 ± 0.2 | 2.1 ± 0.9 | 1.5 ± 0.1 |
| Thyroid | 0.5 ± 0.03 | 1.0 ± 0.5 | 1.4 ± 0.02 | 1.9 ± 0.6 | 1.2 ± 0.1 |
| Muscle | 1.3 ± 0.1 | 1.9 ± 0.4 | 2.6 ± 0.2 | 3.9 ± 1.1 | 2.6 ± 0.3 |
| Bone | 1.0 ± 0.1 | 1.2 ± 0.1 | 3.0 ± 0.1 | 2.2 ± 0.7 | 2.3 ± 0.3 |
| Ascites | 3.30 ± 0.3 | 5.4 ± 1.2 | 12.6 ± 0.4 | 7.8 ± 0.8 | 4.6 ± 0.2 |
% ID/gram ± S.D, n = 6.