Embryonic hematopoietic development. Anatomical sites and timing of hematopoietic cell generation, maintenance, and expansion during embryonic development. Hematopoietic cells are generated de novo in both extra- (yolk sac, allantois, placenta) and intraembryonic (AGM region) tissues. Cells are migrating to other sites for expansion and ultimately long-term maintenance throughout adult life. dpc, days after conception; wpc, weeks after conception.