Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mechanics of lens placode formation. The optic vesicle contacts the surface ectoderm before lens placode formation. Adhesion between the optic vesicle and the pre-lens ectoderm is mediated by extracellular matrix components. The area of contact between the extracellular matrix and the surface ectoderm restricts expansion of the pre-lens domain. Continued cell division in this area leads to cell crowding and cell elongation resulting in placode formation.
