Table 1. Structures of the Pronucleon Peptides PP Used in This Research: Wild Type, AD-315 (Two Point Mutations Indicated in Bold), AD-204, Which Has the Wildtype Composition but the Sequence Is Scrambled.
peptide | sequence | description |
---|---|---|
AD-wildtype | PBA-KLVFF AEDVG SNKGA IIGLM K(PBA)-NH2 | wild type amyloid-β sequence 16–35 |
AD-315 | PBA-KLVFF AEDVG SNKHA IIELM K(PBA)-NH2 | PP two point mutations |
AD-204 | (PBA-NIAD GLEF SIKF KALV GMVG K(PBA)-NH2) | wild type composition, scrambled |