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. Author manuscript; available in PMC: 2014 Jan 1.

Published in final edited form as: Magn Reson Imaging. 2012 Aug 15;31(1):156–161. doi: 10.1016/j.mri.2012.07.005

Fig. 2 — A) Original T2 -w image. Without color mapping the ROI (white arrow) in the human posterior femoral condyle (PFC) presents only subtle structural signal inhomogeneity. *(Cutting artifacts). B) SPGR image with fitted T1ρ color map. ROI in the PFC (sagittal image orientation through the knee) displays T1ρ values up to 120ms (red=abnormal, blue=normal cartilage) as an indicator for extended relaxation times due to an increase in cartilage bound water and a reduction in PG related to catabolic cartilage processes. C) Magnification of the ROI after repeated scanning of the separated PFC. D) Safranin-O stained histo section of a representative sagittal slice through the ROI shows focal PG (red) reduction and a bow-like intrasubstance fissure. The cartilage surface shows only mild irregularities. *(Cutting artifacts)

Fig. 2 — A) Original T2 -w image. Without color mapping the ROI (white arrow) in the human posterior femoral condyle (PFC) presents only subtle structural signal inhomogeneity. *(Cutting artifacts). B) SPGR image with fitted T1ρ color map. ROI in the PFC (sagittal image orientation through the knee) displays T1ρ values up to 120ms (red=abnormal, blue=normal cartilage) as an indicator for extended relaxation times due to an increase in cartilage bound water and a reduction in PG related to catabolic cartilage processes. C) Magnification of the ROI after repeated scanning of the separated PFC. D) Safranin-O stained histo section of a representative sagittal slice through the ROI shows focal PG (red) reduction and a bow-like intrasubstance fissure. The cartilage surface shows only mild irregularities. *(Cutting artifacts)