Table 3.
Regression coefficients and 95% confidence intervals for the association between characteristics of hysterectomy and BMI (kg/m2) at ages 43 and 53 years in the 1946 cohort and at age 44/45 years in the 1958 cohort
| 1946 cohort |
1958 cohort |
|||||
|---|---|---|---|---|---|---|
| N | Regression coefficient (difference in mean BMI at age 43 years) (95% CI) | N | Regression coefficient (difference in mean BMI at age 53 years) (95% CI) | N | Regression coefficient (difference in mean BMI at age 44/45 years) (95% CI) | |
| No hysterectomy or oophorectomy | 1446 | Reference group | 1154 | Reference group | 4032 | Reference group |
| Hysterectomy with oophorectomya | 42 | 0.82 (−0.64, 2.29) | 166 | 0.73 (−0.15, 1.62) | 228 | 1.40 (0.65, 2.15) |
| Hysterectomy no oophorectomy | 103 | 0.70 (−0.26, 1.65) | 148 | 0.89 (−0.05, 1.82) | 217 | 0.96 (0.20, 1.73) |
| Oophorectomy onlya | 16 | −1.11 (−3.46, 1.24) | 20 | 0.77 (−1.65, 3.18) | 63 | −0.82 (−2.22, 0.58) |
| p-Value* | 0.88 | 0.80 | 0.41 | |||
| No hysterectomy or oophorectomy | 1437 | Reference group | 1152 | Reference group | 4032 | Reference group |
| Age at hysterectomy (years) | ||||||
| <40 | 95 | 1.15 (0.16, 2.13) | 87 | 1.12 (−0.06, 2.31) | 255 | 1.37 (0.66, 2.08) |
| 40–44 | 50 | 0.02 (−1.31, 1.36) | 81 | 0.89 (−0.34, 2.11) | 190 | 0.94 (0.13, 1.76) |
| 45–49 | – | – | 100 | 0.55 (−0.56, 1.66) | – | – |
| ≥50 | – | – | 46 | 0.68 (–0.93, 2.28) | – | – |
| p-Value* | 0.17 | 0.90 | 0.43 | |||
| No hysterectomy or oophorectomy | 1437 | Reference group | 1152 | Reference group | – | |
| Hysterectomy for | ||||||
| Fibroids | 36 | 1.28 (−0.29, 2.84) | 105 | 1.25 (0.16, 2.34) | ||
| Menstrual disorders | 51 | 0.29 (−1.04, 1.61) | 98 | 0.52 (−0.60, 1.64) | ||
| Prolapse | 7 | 0.59 (−2.93, 4.11) | 28 | −0.67 (−2.71, 1.37) | ||
| Cancer | 15 | −0.23 (−2.64, 2.18) | 19 | 0.62 (−1.85, 3.08) | ||
| Other reasons | 29 | 1.63 (−0.12, 3.37) | 48 | 1.17 (−0.40, 2.74) | ||
| Unknown reasons | 7 | 0.25 (−3.28, 3.77) | 16 | 1.54 (−1.14, 4.23) | ||
| p-Value* | 0.75 | 0.61 | ||||
| No hysterectomy or oophorectomy | 1437 | Reference group | 1152 | Reference group | – | |
| Route of hysterectomy | ||||||
| Abdominal | 106 | 0.59 (−0.34, 1.53) | 239 | 0.60 (−0.16, 1.35) | ||
| Vaginal | 19 | 2.70 (0.55, 4.84) | 56 | 1.51 (0.05, 2.97) | ||
| Unknown | 20 | −0.19 (−2.28, 1.90) | 19 | 1.48 (−0.98, 3.94) | ||
| p-Value* | 0.13 | 0.45 | ||||
Regression coefficients represent the differences in mean BMI (kg/m2) between the women who had undergone hysterectomy by the time of BMI outcome measurement, categorised by characteristics of hysterectomy, and women who had not undergone hysterectomy or oophorectomy by the time of BMI outcome measurement.
Bilateral or unilateral oophorectomy.
p-Values from likelihood ratio tests comparing model with categorisation of hysterectomy shown with a model in which all hysterectomies were grouped together (women with oophorectomy only excluded from all models except those examining oophorectomy status).