Table 2. Transcription factors predicted to have their binding sites in the vicinity (±100 bp) of the p53-binding sites.

Commmon for induced and repressed				Unique for induced				Unique for Repressed
Factor	N sites per 1 kbp	Enrich	P-value	Factor	N sites per 1 kbp	Enrich	P-value	Factor	N sites per 1 kbp	Enrich	P-value
AHR	0.7117	1.8792	0.001829	BACH2	0.2491	2.587	0.0098112	ARNT	1.7143	2.811	3.59E-05
AP2	5.1246	3.1678	9.43E-40	ETV7	2.9181	1.3733	0.0006481	BCL6	2.0714	1.9207	0.0017116
AP4	1.2278	1.6777	0.0006008	HAND1	4.1815	1.494	7.40E-07	DEAF1	0.2143	33.38	0.0021042
AR	0.3559	2.1322	0.0095111	HNF1A	0.1779	3.9597	0.0049341	HIF1A	1.2143	2.6642	0.0007813
CP2	4.7865	1.6139	7.10E-10	AP1	0.4804	2.5806	0.0004129
CREB/ATF	1.9217	1.7404	7.09E-06	MAF	0.1779	6.9295	0.0005729
E2F	1.2278	3.4153	1.15E-11	MAZ	0.7117	2.174	0.0002464
EBF	0.9431	2.2258	1.73E-05	MYOG	5.8541	1.416	2.89E-07
EGR1	0.8363	3.7221	3.98E-09	NFKB	1.121	1.7289	0.0005755
ETS1	1.3701	2.1558	6.09E-07	NR3C1	0.1068	16.631	0.0018787
HIC1	0.4804	3.7419	7.46E-06	PAX6	8.2206	1.177	0.0020025
NR5A2	1.1744	1.5373	0.0037999	SMAD3	4.6085	1.2729	0.0008693
PAX3	5.8363	1.2877	0.0001103	SP3	4.2705	1.974	3.22E-15
PAX4	1.2811	1.5234	0.0030804	ZBTB33	0.2491	2.985	0.0044078
PAX5	6.9751	1.6266	5.52E-14
PPARA	6.4057	1.2319	0.000642
SP1	1.1566	5.4596	2.06E-16
STAT	2.2143	1.8347	0.0022804
TEAD-2	1.2989	3.0658	7.00E-11
TP53	3.2562	8.0514	4.66E-55
V-MYB	0.8541	2.2174	4.48E-05
VDR	4.7687	1.6693	6.62E-11
WT1	7.0463	2.3304	8.54E-34
ZBTB7A	10.854	1.6118	3.70E-20
ZF5	7.8114	3.3521	6.24E-64
ZFP67	0.7651	11.919	1.58E-16
ZIC3	7.8114	1.4215	2.58E-09

Expression level after nutlin3a treatment: underlined – induced; bold – repressed; plain – no changes.