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. 2012 Oct 1;287(48):40391–40399. doi: 10.1074/jbc.M112.402420

FIGURE 8.

FIGURE 8.

AP-1 activity and TLR4 expression in HK-2 cells exposed to c-Jun and c-Fos siRNA knockdown and IL-18 stimulation in vitro. A, cell lysate AP-1 DNA binding activity following 3 days of cell exposure to varying concentrations of recombinant human IL-18 (0–100 ng/ml). B, quantitative cell lysate TLR4 mRNA expression represented as percentages of GAPDH following 3 days of cell exposure to recombinant human IL-18 (100 ng/ml) in the presence or absence of a c-Jun siRNA (40 pmol) or c-Fos siRNA (40 pmol).