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Combination treatment with HP-2 or HP-14, and cisplatin. TGCT cells were treated with HP-2 or HP-14 and 1 μℳ cisplatin for 48 h, and the proliferation was measured in 2102EP (A, B), 2102EP-R (C, D) and in Caki-1 (E, F). The combination of HP-2 and HP-14 with cisplatin led to additive growth-inhibitory effects in TGCT cells 2102EP and 2102EP-R, whereas no marked growth inhibition was observed in the VEGFR-2-negative renal cell carcinoma cell line Caki-1.
