Figure 1.
The effect of bortezomib on MM cells viability and telomerase activity. (A) The effect of bortezomib on cells viability. MM cell lines, ARP-1, CAG, RPMI 8226, and U266 were exposed to bortezomib at the indicated concentrations for 24 and 48 h, and their viability was assessed by the WST-1 assay. 8226, RPMI 8226. The IC50 of each cell line is depicted below the graphs. (B) The effect of bortezomib on telomerase activity. ARP-1, CAG, RPMI 8226, and U266 cells were exposed to the indicated bortezomib concentrations for 24 and 48 h. Telomerase activity was measured by the TRAP assay.