Table 1.
mRNA and protein expression correlations in various organisms.
| Organism | N | R2 | References |
|---|---|---|---|
| SINGLE CELL mRNA vs. PROTEIN | |||
| Escherichia coli | 1 | ~0.01a | Taniguchi et al., 2010 |
| SINGLE CELL mRNA vs. mRNA | |||
| Mus musculus (Oocyte) | 21,436 | 0.92b | Tang et al., 2009 |
| Homo sapiens (HeLa) | ~29,000 | 0.75–0.78 | Fan et al., 2012 |
| Homo sapiens (Brain tumor) | ~29,000 | 0.70–0.77 | Fan et al., 2012 |
| SINGLE CELL PROTEIN vs. PROTEIN | |||
| Homo sapiens (Macrophage) | 12 | ~0.72b | Shin et al., 2011 |
| CELL POPULATION mRNA vs. PROTEIN | |||
| Escherichia coli | 841 | 0.29 | Taniguchi et al., 2010 |
| 437 | 0.47 | Lu et al., 2007 | |
| Desulfovibrio vulgaris | 392–427 | 0.20–0.28 | Nie et al., 2006 |
| Saccharomyces | 71 | 0.58 | Futcher et al., 1999 |
| cerevisiae | 328 | 0.01a,b–0.36b | Fournier et al., 2010 |
| Schizosaccharomyces pombe | 1367 | 0.34 | Schmidt et al., 2007 |
| Streptomyces coelicolor | 884 | 0.40 | Jayapal et al., 2008 |
| Mus musculus (NIH/3T3) | 5028 | 0.31b–0.41 | Schwanhäusser et al., 2011 |
| Homo sapiens (Medulloblastoma) | 511 | 0.22 | de Sousa Abreu et al., 2009 |
| CELL POPULATION mRNA vs. mRNA | |||
| Mycobacterium tuberculosis | 3989 | 0.9 | Ward et al., 2008 |
| Mus musculus (NIH/3T3) | 5028 | 0.91b | Schwanhäusser et al., 2011 |
| CELL POPULATION PROTEIN vs. PROTEIN | |||
| Porphyromonas gingivalis | 751 | 0.97–0.99 | Xia et al., 2007 |
| Glycine max (Soybean) | 163–287 | 0.9 | Brandão et al., 2010 |
| Mus musculus (NIH/3T3) | 5028 | 0.90b | Schwanhäusser et al., 2011 |
a
Corresponding mutual information I ~ 0.
b
Values we computed from raw data.