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. Author manuscript; available in PMC: 2012 Nov 23.
Published in final edited form as: Mod Pathol. 2012 May 25;25(10):1364–1377. doi: 10.1038/modpathol.2012.89

Table 2.

The relationships between tumor thickness and submucosal invasion thickness versus the depth of invasion level and the presence of lymph node metastasis in the total 271 patients

Characteristics Total m2 m3 sm1 sm2 sm3 Lymph node
metastasis (%)
Total 271 22 30 23 55 141 53 (20)
Tumor thickness
<1000µm 19 13 5 1 0 0 0 (0)
≥1000µm and <2000µm 36 6 11 8 9 2 2 (6)
≥2000µm and <3000µm 43 3 5 4 20 11 4 (9)
≥3000µm and <4000µm 45 0 2 6 11 26 11 (24)
≥4000µm and <5000µm 28 0 1 1 6 20 9 (32)
≥5000µm and <6000µm 31 0 0 0 3 28 10 (32)
≥6000µm and <7000µm 22 0 1 0 1 20 5 (23)
≥7000µm and <10000µm 24 0 1 2 1 20 5 (21)
≥10000µm 23 0 4 1 4 14 7 (30)
Submucosal invasion thickness
Not beyond muscularis mucosae 52 22 30 0 0 0 2 (4)
<500µm 20 0 0 16 4 0 2 (10)
≥500µm and <1000µm 29 0 0 3 20 6 4 (14)
≥1000µm and <1500µm 30 0 0 1 17 12 4 (13)
≥1500µm and <2000µm 25 0 0 0 6 19 4 (16)
≥2000µm and <2500µm 23 0 0 1 2 20 8 (35)
≥2500µm and <3000µm 26 0 0 1 2 23 8 (31)
≥3000µm and <4000µm 27 0 0 1 3 23 5 (19)
≥4000µm and <5000µm 20 0 0 0 1 20 10 (50)
≥5000µm 19 0 0 0 0 19 6 (32)
Lymph node metastasis (%) 0 2(7) 4(17) 7(13) 40(28)