Table 2.
The number of tagSNPs genotyped in this study along with the number of the SNPs captured with these tagSNPs for each gene
| No. | Gene | Chromosome | Size (kbp)* | Number of Genotyped tagSNPs, n |
Number of Captured SNPs, n (%)† |
Mean Max r2 |
|---|---|---|---|---|---|---|
| 1 | ERCC2 | 19 | 29 | 8 | 18/20 (90) | 0.97 |
| 2 | ADH1B | 4 | 10 | 3 | 4/4 (100) | 1.00 |
| 3 | ALDH2 | 12 | 53 | 10 | 22/23 (95) | 0.95 |
| 4 | CCND1 | 11 | 23 | 2 | 2/2 (100) | 1.00 |
| 5 | CDKN2A | 9 | 18 | 6 | 8/8 (100) | 0.99 |
| 6 | CYP1A1 | 15 | 16 | 1 | 1/1 (100) | 1.00 |
| 7 | CYP2E1 | 10 | 22 | 6 | 27/34 (79) | 0.97 |
| 8 | ECRG1 | 4 | 63 | 9 | 49/54 (90) | 0.99 |
| 9 | GSTP1 | 11 | 13 | 4 | 12/12 (100) | 0.99 |
| 10 | MGMT | 10 | 310 | 49 | 321/332 (96) | 0.95 |
| 11 | MTHFR | 1 | 30 | 8 | 35/36 (97) | 0.99 |
| 12 | NAT2 | 8 | 20 | 10 | 40/46 (86) | 0.94 |
| 13 | OGG1 | 3 | 27 | 5 | 5/5 (100) | 1.00 |
| 14 | TP53 | 17 | 29 | 6 | 7/14 (50) | 1.00 |
| 15 | XRCC1 | 19 | 42 | 14 | 43/44 (97) | 0.93 |
| Total | 705 | 141 | 594/635 (94) | 0.98 | ||
*
The size of the gene including 5 kbp at each end for covering gene regulatory regions
†
In this column the number of the SNPs with MAF >1% identified in the Chinese population of the HapMap project and the proportion of these SNPs which is captured by the genotyped tagSNPs in this study are shown for each gene.