Table 4.
Genotyping results of the Arg48His variant of ADH1B gene on the joint sample set
| Turkmens, n (%) | Non-Turkmen, n (%) | Total samples, n (%) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases (281) | Controls (811) | OR* | P-Value* | Cases (465) | Controls (562) | OR* | P-Value* | Cases (746) | Controls (1373) | OR* | P-Value* | |
| Arg/Arg | 190 (67.6) | 488 (60.2) | 1.00 | 1.00 | 300 (64.5) | 339 (60.3) | 1.00 | 1.00 | 490 (65.7) | 827 (60.2) | 1.00 | 1.00 |
| Arg/His | 80 (28.5) | 288 (35.5) | 0.72 | 0.03 | 152 (32.7) | 183 (32.5) | 0.92 | 0.58 | 232 (31.1) | 471 (34.3) | 0.84 | 0.10 |
| His/His | 8 (2.8) | 34 (4.2) | 0.72 | 0.11 | 13 (2.8) | 39 (6.9) | 0.57 | 0.0006 | 21 (2.8) | 73 (5.3) | 0.63 | 0.0002 |
| Dominant | 0.69 | 0.02 | 0.81 | 0.13 | 0.77 | 0.01 | ||||||
| Recessive | 0.59 | 0.19 | 0.33 | 0.0007 | 0.41 | 0.0004 | ||||||
*
P-value and odds ratio (OR) were adjusted for age in Turkmens and for age and ethnicity for Non-Turkmens and total samples using multivariate logistic regression analysis.