Reagents and conditions:
(a) KI, K2CO3, acetone, reflux, 18 h. (b) NaOH,
ethanol, reflux, 2 h. (c) HCl, water. (d) DCC, DMAP, CH2Cl2, reflux, 18 h. (e) Silica gel, dichloromethane–toluene–ethyl
acetate (75:25:1). (f) H2, 10% Pd/C, THF, 40 °C, 16
h. (g) 5% Na2CO3, rt, 6 h.