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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Future Virol. 2012 Jul 1;7(7):719–728. doi: 10.2217/fvl.12.58

Figure 3. T-cell production of IL-22 was significantly different between resolved and chronic HCV subjects.

Figure 3

(A) Peripheral blood mononuclear cells from resolved (n = 8) and chronic (n = 8) subjects were incubated with either medium, rNS3 (0.1, 1 and 10 μg/ml), H3 (3 μg/ml), H5 (3 μg/ml) or phytohemagglutinin (2 μg/ml). Cell culture supernatants were collected 48 h after the addition of antigens, mitogen or medium. Data are normalized to medium. (B) Representative flow cytometry dot plots of CD3+ IL-22+ expression in a resolved HCV subject’s cells at 48 h post-antigen stimulation. Flow cytometry data are representative of four different experiments.

*p < 0.05, Student’s paired t test.

rNS3: Recombinant NS3.