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. 2012 May 4;12:62. doi: 10.1186/1472-6882-12-62

Table 2.

Effects of different treatments on damage score, extension of lesion, changes in colon weight, adherences to adjacent organs and microscopic score

Experimental Groups Scorea(0–10) Extension of lesionb(cm) Colon weightb(mg/cm) Adherence(%) Microscopic Score (0-27)a
Non-colitic groups
 
 
 
 
 
Non treated
0***
0**
112.68 ± 6.28**
0**
0**
20% diet
0***
0**
113.63 ± 5.56**
0*
0**
Colitic groups
 
 
 
 
 
TNBS-Control
7 (4–8)
3.04 ± 0.33
260.63 ± 37.62
60
10.5 (5–19)
5% diet
6 (0–7)
1.67 ± 0.42*
156.67 ± 16.76*
15*
8 (5–15)
10% diet
5 (4–6)
1.45 ± 0.29*
169.24 ± 6.12*
0*
5 (3–11)
20% diet
6 (4–8)
2.17 ± 0.36
204.75 ± 22.81
85
4 (2–10)
5% diet + prednisolone
7 (5–10)
3.24 ± 0.59
196.73 ± 23.22
15*
5 (2–14)
10% diet + prednisolone
6 (5–7)
2.43 ± .029
156.01 ± 9.87*
45
7 (2–11)
20% diet + prednisolone
6 (0–8)
2.41 ± 0.68
258.04 ± 63.77
45
5 (1–9)
prednisolone 3 (0–4)* 1.40 ± 0.27* 162.20 ± 8.14* 45 11.0 (8–14)

a Score and microscopic score data are expressed as median (range) and were statically evaluated by non-parametric Kruskal-Wallis test; b Extension of lesion and colonic weight data are expressed as mean ± SEM values and differences were assessed using ANOVA was followed by post hoc test of Dunnet; Adherence was expressed in percentage and was analyzed with the χ2 test. *P < 0.05, P < 0.01 and P < 0.001 versus TNBS control group.

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