Table 2.
Adalimumab with MTX | Adalimumab without MTX | |||||
---|---|---|---|---|---|---|
Mean baseline value | Mean visit value | Mean % change | Mean baseline value | Mean visit value | Mean % change | |
Week 16 | ||||||
PhGA (mm) | 55.8 | 20.6 | −64.8 | 58.6 | 10.6 | −83.8 |
PaGA (mm) | 44.7 | 22.1 | −50.5 | 48.6 | 15.4 | −74.5 |
AJC73 | 11.0 | 3.8 | −59.9 | 13.6 | 3.2 | −80.3 |
LOM69 | 7.5 | 3.7 | −38.3 | 5.8 | 1.6 | −76.7 |
CHAQ | 0.7 | 0.4 | −32.8 | 0.7 | 0.4 | −35.7 |
CRP (mg/dL) | 0.9 | 0.3 | −23.8 | 3.6 | 1.7 | −65.1 |
Week 60 | ||||||
PhGA (mm) | 55.0 | 16.7 | −74.0 | 58.6 | 12.8 | −81.5 |
PaGA (mm) | 42.9 | 16.6 | −51.7 | 48.6 | 27.0 | −48.6 |
AJC73 | 11.1 | 1.9 | −81.5 | 13.6 | 3.0 | −79.8 |
LOM69 | 7.6 | 1.5 | −78.7 | 5.8 | 2.4 | −72.2 |
CHAQ | 0.7 | 0.2 | −46.9 | 0.7 | 0.5 | −41.0 |
CRP (mg/dL) | 1.0 | 0.4 | −46.6 | 3.6 | 1.4 | −4.0 |
AJC active joint count, CHAQ Childhood Health Assessment Questionnaire, CRP C-reactive protein, LOM limitation of motion, MTX methotrexate, PaGA Patient’s Global Assessment, PhGA, Physician’s Global Assessment