Fig. 7.

Increased NO bioavailability attenuates GC-dependent signaling. Western blots showing the levels of p-VASP and total VASP in WT and ecSOD hearts. VASP phosphorylation status was used as a measure of GC-dependent signaling. p-VASP and VASP were measured in whole heart (left panels) and myocyte (right panels) homogenates from WT and ecSOD Tg mice by Western analysis. Values are the mean ± SEM (n = 2–4). *P < 0.05