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. 2012 Sep 2;119(12):1507–1510. doi: 10.1007/s00702-012-0894-8

Table 1.

Studies showing higher concentration of iron in PD substantia nigra compared to control

Author (year) Method No of PD samples No of control samples PD/control ratio
Earle (1968) XFS 11 ? 2 ± ?
Sofic et al. (1988) SPH 8 8 1.77 ± 0.37
Griffiths and Crossman (1993) AA 6 6 2.01 ± 0.24
Mann et al. (1994) ICP 18 22 1.56 ± 0.69
Dexter et al. (1989) ICP 7 9 1.34 ± 0.17

PD/control was calculated with the standard error of the ratio

XFS X-ray fluorescent spectroscopy, SPH spectrophotometry, AA atomic absorption, ICP inductively coupled plasma spectroscopy