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. 2012 May 31;3(4):225–237. doi: 10.1007/s13539-012-0069-3

Fig. 4.

Fig. 4

Use of mTOR and calcineurin inhibitors as maintenance immunosuppression after liver transplantation. This does not include the use of steroids alone which also contributes to sarcopenia. mTOR inhibitors result in impaired muscle protein synthesis as well as autophagy, both of which could aggravate sarcopenia after liver transplantation. Data compiled from OPTN / SRTR 2009 Annual Data Report. HHS/HRSA/HSB/DOT. http://optn.transplant.hrsa.gov/ar2009/data_tables_section9.htm