TABLE 1.
Yeast NuA4 subunit | Human homolog(s) | Domain(s)a |
---|---|---|
Tra1 | TRRAP (transformation/transcription domain-associated protein) | PI-3 kinase/ATM |
Eaf1 | hDomino? (p400) | SANT, HSA |
Epl1 | Enhancer of Polycomb (EPC1, EPC-like) | EpcA |
Eaf2 | DMAP1 (DNMT1-associated protein) | SANT |
Arp4 | BAF53a (BRG1-associated factor) | Actin related |
Esa1 | Tip60/Tip60b (Tat interactive protein) | Chromodomain/MYST HAT |
Eaf3 | Mortality factor related genes (MORF4, MRG15/X) | Chromodomains |
Act1 | Actin | |
Yng2 | Inhibitor of growth gene family (ING1 to -5) | PHD finger |
Eaf5 | ? | |
Yaf9 | YEATS family (AF9, ENL, GAS41) | YEATS |
Eaf6 | hEaf6 (FLJ11730) |
PI-3 kinase, phosphatidylinositol 3-kinase.